287458

• Gene Symbol: Six2
• Gene Name: sine oculis-related homeobox 2
• Gene Aliases: -
• Chromosome Location: Chr.17: 85662735 - 85688254 on Build GRCm38
• UniGene ID: Mm.5039
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Six2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011380.2	NP_035510.1	1	433
GenBank mRNA	BC068021.1	-	1	433	6394139
	D83147.1	-	1	426
	X80338.1	-	1	206

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191908.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

metanephros development
kidney development
chondrocyte differentiation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein import into nucleus
multicellular organism development
mesodermal cell fate specification
cell proliferation
anterior/posterior axis specification
cell migration
regulation of ossification
regulation of chondrocyte differentiation
middle ear morphogenesis
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
embryonic skeletal system morphogenesis
nephron development
nephron morphogenesis
mesenchymal stem cell maintenance involved in nephron morphogenesis
mesenchymal cell differentiation involved in kidney development
regulation of branching involved in ureteric bud morphogenesis
mesenchymal stem cell proliferation
positive regulation of chondrocyte proliferation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein complex binding
sequence-specific DNA binding