287460

• Gene Symbol: Six3
• Gene Name: sine oculis-related homeobox 3
• Gene Aliases: E130112M24Rik, Six3a, Six3alpha, Six3b, Six3beta
• Chromosome Location: Chr.17: 85620834 - 85626191 on Build GRCm38
• UniGene ID: Mm.370208
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Six3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011381.4	NP_035511.2	1	642
GenBank mRNA	BC094426.1	-		445	6855602
	BC098096.1	-	1	262	6402835
	BF467709.1	-	1	280
	D83144.1	-	1	903
	D83145.1	-	1	228
	X90871.1	-		417

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_005413, AL162671, AJ012611, BC030289.
This siRNA also targets the following transcripts in Rat: NM_023990, AB030833.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
eye development
epithelial cell maturation
lens development in camera-type eye
optic vesicle morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein import into nucleus
multicellular organism development
brain development
proximal/distal axis specification
neuroblast differentiation
diencephalon development
telencephalon development
forebrain anterior/posterior pattern specification
forebrain dorsal/ventral pattern formation
cell proliferation in forebrain
telencephalon regionalization
pituitary gland development
negative regulation of Wnt signaling pathway
regulation of cell proliferation
camera-type eye development
negative regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
circadian behavior
lens induction in camera-type eye
regulation of neural retina development
lens fiber cell differentiation
neuroblast migration
regulation of cell cycle phase transition
regulation of neuroblast proliferation
apoptotic process involved in development
lens fiber cell apoptotic process
regulation of neural precursor cell proliferation

Function(s)

RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription corepressor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
receptor binding
protein binding
histone deacetylase binding
sequence-specific DNA binding