288570

• Gene Symbol: ILK
• Gene Name: integrin linked kinase
• Gene Aliases: HEL-S-28, ILK-1, ILK-2, P59, p59ILK
• Chromosome Location: Chr.11: 6603708 - 6610874 on Build GRCh38
• UniGene ID: Hs.706355
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ILK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001014794.2	NP_001014794.1	2	175
	NM_001014795.2	NP_001014795.1	1	476
	NM_001278441.1	NP_001265370.1	2	221
	NM_001278442.1	NP_001265371.1	2	175
	NM_004517.3	NP_004508.1	2	221
	XM_005252904.4	XP_005252961.1	2	182
	XM_005252905.2	XP_005252962.1	2	187
	XM_011520065.1	XP_011518367.1	2	181
	XM_017017672.1	XP_016873161.1	2	132
GenBank mRNA	AB209416.1	-	1	476
	AK293474.1	-	2	152
	AK296628.1	-	2	142
	AK314843.1	-	2	156
	BC001554.1	-	2	82	3457801
	CB113885.1	-	2	198
	CR407673.1	-	1	14
	CR749220.1	-	1	470
	DC379936.1	-	1	476
	DC380243.1	-	2	175
	EU794625.1	-	1	309
	U40282.1	-	2	170

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133409, AF329194, BC062406.
This siRNA also targets the following transcripts in Mouse: NM_010562, NM_001161724, AK154207, CA752166, BC003737, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

branching involved in ureteric bud morphogenesis
positive regulation of cell-matrix adhesion
outflow tract morphogenesis
protein phosphorylation
negative regulation of protein kinase activity
cell cycle arrest
cell-matrix adhesion
integrin-mediated signaling pathway
cell aging
cell proliferation
positive regulation of cell proliferation
negative regulation of cardiac muscle cell apoptotic process
fibroblast migration
negative regulation of smooth muscle cell migration
peptidyl-serine phosphorylation
nerve development
myelination in peripheral nervous system
positive regulation of cell migration
positive regulation of BMP signaling pathway
myelin assembly
regulation of actin cytoskeleton organization
cell junction assembly
substrate adhesion-dependent cell spreading
positive regulation of phosphorylation
extracellular fibril organization
positive regulation of MAP kinase activity
protein kinase B signaling
negative regulation of neuron apoptotic process
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of myoblast differentiation
positive regulation of osteoblast differentiation
positive regulation of axon extension
positive regulation of transcription, DNA-templated
negative regulation of smooth muscle cell proliferation
neuron projection morphogenesis
positive regulation of dendrite morphogenesis
protein heterooligomerization
positive regulation of protein kinase B signaling
platelet aggregation
positive regulation of canonical Wnt signaling pathway
negative regulation of neural precursor cell proliferation

Function(s)

protein serine/threonine kinase activity
signal transducer activity
integrin binding
protein binding
ATP binding
SH3 domain binding
protein kinase binding