288574

• Gene Symbol: DNM2
• Gene Name: dynamin 2
• Gene Aliases: CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5
• Chromosome Location: Chr.19: 10718053 - 10831910 on Build GRCh38
• UniGene ID: Hs.211463
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DNM2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001005360.2	NP_001005360.1	16	1929
	NM_001005361.2	NP_001005361.1	16	1929
	NM_001005362.2	NP_001005362.1	15	1917
	NM_001190716.1	NP_001177645.1	16	1929
	NM_004945.3	NP_004936.2	15	1917
GenBank mRNA	AK023207.1	-	9	866
	AK094984.1	-	2	1321
	AK097875.1	-	8	564
	AK097989.1	-	2	752
	AK124881.1	-	2	3238
	AK126192.1	-	2	1899
	AK127033.1	-	2	3927
	AK289831.1	-	15	1762
	AK295929.1	-	10	983
	AK312260.1	-	16	1903
	BC039596.1	-	16	1819	5722134
	BC054501.1	-	15	1877	6473791
	L36983.1	-	15	1871

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013199, XM_006242613, XM_006242612, XM_008765918, XM_006242608, and others.
This siRNA also targets the following transcripts in Mouse: NM_001253894, NM_001253893, NM_007871, NM_001039520, L31398, and others.

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
G-protein coupled receptor internalization
ventricular septum development
regulation of transcription, DNA-templated
Golgi to plasma membrane transport
endocytosis
receptor-mediated endocytosis
phagocytosis
signal transduction
spermatogenesis
response to light stimulus
positive regulation of lamellipodium assembly
antigen processing and presentation of exogenous peptide antigen via MHC class II
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of axon extension
receptor internalization
transferrin transport
regulation of Rac protein signal transduction
aorta development
response to cocaine
positive regulation of apoptotic process
macropinocytosis
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription, DNA-templated
synaptic vesicle transport
neuron projection morphogenesis
positive regulation of phagocytosis
regulation of nitric-oxide synthase activity
cilium morphogenesis
coronary vasculature development
cellular response to carbon monoxide
cellular response to X-ray
cellular response to nitric oxide
positive regulation of substrate adhesion-dependent cell spreading
cellular response to dopamine
regulation of Golgi organization
positive regulation of sodium:potassium-exchanging ATPase activity
negative regulation of membrane tubulation

Function(s)

GTPase activity
protein binding
GTP binding
microtubule binding
SH3 domain binding
enzyme binding
protein kinase binding
D2 dopamine receptor binding
protein complex binding
phosphatidylinositol 3-kinase regulatory subunit binding
WW domain binding
nitric-oxide synthase binding