2886

• Gene Symbol: MSH6
• Gene Name: mutS homolog 6
• Gene Aliases: GTBP, GTMBP, HNPCC5, HSAP, p160
• Chromosome Location: Chr.2: 47783082 - 47806953 on Build GRCh38
• UniGene ID: Hs.445052
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MSH6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000179.2	NP_000170.1	2	437
	NM_001281493.1	NP_001268422.1	2	437
	NM_001281494.1	NP_001268423.1	2	176
	XM_011532798.1	XP_011531100.1	2	144
	XM_011532799.1	XP_011531101.1	2	219
GenBank mRNA	AK304735.1	-	2	176
	AK308392.1	-	2	336
	BC071594.1	-	2	440
	BC104665.1	-	2	359
	D89646.1	-	2	368
	DA857066.1	-	2	414
	U28946.1	-	2	372
	U54777.2	-	2	355

More Information

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

meiotic mismatch repair
DNA repair
mismatch repair
reciprocal meiotic recombination
determination of adult lifespan
intrinsic apoptotic signaling pathway in response to DNA damage
response to UV
viral process
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
maintenance of DNA repeat elements
isotype switching
positive regulation of isotype switching
negative regulation of DNA recombination
positive regulation of helicase activity
intrinsic apoptotic signaling pathway

Function(s)

magnesium ion binding
four-way junction DNA binding
chromatin binding
double-stranded DNA binding
protein binding
ATP binding
ATPase activity
mismatched DNA binding
guanine/thymine mispair binding
single guanine insertion binding
single thymine insertion binding
oxidized purine DNA binding
MutLalpha complex binding
methylated histone binding
protein homodimerization activity
ADP binding