290144

• Gene Symbol: KCNH2
• Gene Name: potassium voltage-gated channel subfamily H member 2
• Gene Aliases: ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1
• Chromosome Location: Chr.7: 150944956 - 150978314 on Build GRCh38
• UniGene ID: Hs.647099
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: KCNH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000238.3	NP_000229.1	6	1827
	NM_001204798.1	NP_001191727.1	2	732
	NM_172056.2	NP_742053.1	6	1827
	NM_172057.2	NP_742054.1	2	732
	XM_011516185.2	XP_011514487.1	5	1238
	XM_011516186.2	XP_011514488.1	6	1819
	XM_017012195.1	XP_016867684.1	5	1908
	XM_017012196.1	XP_016867685.1	6	1368
GenBank mRNA	AB044806.1	-	6	1609
	AF363636.1	-	6	1426
	AJ512214.1	-	2	423
	AJ609614.1	-	2	406
	BC001914.1	-	5	1083
	BC127673.1	-	2	721
	BQ890248.1	-	2	732
	BT007336.1	-	5	1078
	DQ525913.1	-	6	1827
	FJ938021.1	-	4	2259
	U04270.1	-	6	1609

More Information

Panther Classification:

Molecular Function -

ion channel

Gene Ontology Categories:

Process(es)

phosphorelay signal transduction system
regulation of heart rate by hormone
signal transduction by protein phosphorylation
cellular response to drug
regulation of membrane potential
potassium ion homeostasis
cardiac muscle contraction
regulation of membrane repolarization
regulation of ventricular cardiac muscle cell membrane repolarization
cardiac conduction
potassium ion export
potassium ion transmembrane transport
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane repolarization during action potential
membrane repolarization during cardiac muscle cell action potential
regulation of heart rate by cardiac conduction
potassium ion export across plasma membrane
membrane repolarization during ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transport
negative regulation of potassium ion transmembrane transport
positive regulation of potassium ion transmembrane transport
negative regulation of potassium ion export

Function(s)

phosphorelay sensor kinase activity
inward rectifier potassium channel activity
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
protein binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
C3HC4-type RING finger domain binding
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
scaffold protein binding
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization