290212

• Gene Symbol: EXOSC8
• Gene Name: exosome component 8
• Gene Aliases: CIP3, EAP2, OIP2, PCH1C, RRP43, Rrp43p, bA421P11.3, p9
• Chromosome Location: Chr.13: 37000373 - 37009614 on Build GRCh38
• UniGene ID: Hs.294041
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EXOSC8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_181503.2	NP_852480.1	7	639
	XM_006719763.1	XP_006719826.1	6	770
GenBank mRNA	AF025438.1	-	6	368
	AF279901.1	-	8	430
	AK096810.1	-	5	2279
	AK126602.1	-	1	824
	AL050353.1	-	6	1862
	BC020773.1	-	7	400	4808747

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106432, XM_006232332, FQ230358.

Panther Classification:

Molecular Function -

RNA metabolism protein, exoribonuclease, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
biological_process
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
U1 snRNA 3'-end processing
U4 snRNA 3'-end processing
U5 snRNA 3'-end processing
regulation of mRNA stability
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
nuclear mRNA surveillance
nuclear polyadenylation-dependent rRNA catabolic process
nuclear polyadenylation-dependent tRNA catabolic process
nuclear polyadenylation-dependent mRNA catabolic process

Function(s)

exoribonuclease activity
protein binding
AU-rich element binding