2933

• Gene Symbol: VAV1
• Gene Name: vav guanine nucleotide exchange factor 1
• Gene Aliases: VAV
• Chromosome Location: Chr.19: 6772668 - 6857366 on Build GRCh38
• UniGene ID: Hs.116237
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: VAV1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001258206.1	NP_001245135.1	2, 3	469
	NM_001258207.1	NP_001245136.1	2, 3	469
	NM_005428.3	NP_005419.2	2, 3	469
	XM_005259642.1	XP_005259699.1	2, 3	429
GenBank mRNA	AK225710.1	-	2, 3	423
	AK301128.1	-	2, 3	179
	AK313307.1	-	2, 3	411
	BC013361.2	-	2, 3	249	3842829
	X16316.1	-	1, 2	295

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012759, BC091160, U39476.
This siRNA also targets the following transcripts in Mouse: NM_001163816, NM_001163815, NM_011691, AK154183, AK153052, and others.

Gene Ontology Categories:

Process(es)

regulation of transcription, DNA-templated
immune response
G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
small GTPase mediated signal transduction
regulation of cell size
regulation of phosphatidylinositol 3-kinase signaling
platelet activation
T cell differentiation
neutrophil chemotaxis
T cell costimulation
regulation of Rho protein signal transduction
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of apoptotic process
regulation of GTPase activity
positive regulation of GTPase activity
positive regulation of natural killer cell mediated cytotoxicity
phosphatidylinositol phosphorylation
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
regulation of small GTPase mediated signal transduction
reactive oxygen species metabolic process

Function(s)

transcription factor activity, sequence-specific DNA binding
guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
Rac guanyl-nucleotide exchange factor activity
metal ion binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity