300 Validated

• Gene Symbol: PRKCA
• Gene Name: protein kinase C alpha
• Gene Aliases: AAG6, PKC-alpha, PKCA, PRKACA
• Chromosome Location: Chr.17: 66302640 - 66810744 on Build GRCh38
• UniGene ID: Hs.531704
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PRKCA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002737.2	NP_002728.1	2, 3	242
	XM_017024836.1	XP_016880325.1	2, 3	410
	XM_017024841.1	XP_016880330.1	2, 3	410
GenBank mRNA	AB209475.1	-	2, 3	190
	AB451258.1	-	2, 3	198
	AB451383.1	-	2, 3	198
	AY633609.1	-	2, 3	203
	BC053321.1	-	2, 3	414
	BC109273.1	-	2, 3	224	40028305
	BC109274.1	-	2, 3	224	40028308
	M22199.1	-	2, 3	157
	X52479.1	-	2, 3	225

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001105713, XM_008768310, BC169007, X07286.
This siRNA also targets the following transcripts in Mouse: NM_011101, M25811, X52684, X52685, BC096493, and others.

Matching Taqman Gene Expression Assay:

Hs00176973_m1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

angiogenesis
positive regulation of endothelial cell proliferation
desmosome assembly
protein phosphorylation
mitotic nuclear envelope disassembly
cell adhesion
activation of adenylate cyclase activity
negative regulation of adenylate cyclase activity
positive regulation of endothelial cell migration
positive regulation of cardiac muscle hypertrophy
peptidyl-serine phosphorylation
platelet activation
positive regulation of cell migration
positive regulation of lipopolysaccharide-mediated signaling pathway
negative regulation of glial cell apoptotic process
histone H3-T6 phosphorylation
intracellular signal transduction
regulation of mRNA stability
positive regulation of blood vessel endothelial cell migration
positive regulation of macrophage differentiation
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of mitotic cell cycle
regulation of insulin secretion
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
regulation of platelet aggregation
apoptotic signaling pathway
positive regulation of dense core granule biogenesis

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
calcium-dependent protein kinase C activity
protein binding
ATP binding
zinc ion binding
enzyme binding
histone kinase activity (H3-T6 specific)