3013

• Gene Symbol: CBL
• Gene Name: Cbl proto-oncogene
• Gene Aliases: C-CBL, CBL2, FRA11B, NSLL, RNF55
• Chromosome Location: Chr.11: 119206276 - 119308149 on Build GRCh38
• UniGene ID: Hs.504096
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CBL
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005188.3	NP_005179.2	6, 7	1153
	XM_011543057.2	XP_011541359.1	6, 7	1153
	XM_017018511.1	XP_016874000.1	5, 6	588
GenBank mRNA	BC132733.1	-	6, 7	1082	40146755
	BC136463.1	-	6, 7	1082	9020452
	X57110.1	-	6, 7	1159

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_576396, XM_006242965.
This siRNA also targets the following transcripts in Mouse: NM_007619, AK153915, AK029826, BC125285, AK163907, and others.

Panther Classification:

Molecular Function -

ligase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

regulation of transcription, DNA-templated
cell surface receptor signaling pathway
epidermal growth factor receptor signaling pathway
transforming growth factor beta receptor signaling pathway
fibroblast growth factor receptor signaling pathway
positive regulation of phosphatidylinositol 3-kinase signaling
protein ubiquitination
negative regulation of epidermal growth factor receptor signaling pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of receptor-mediated endocytosis
cell-cell adhesion

Function(s)

phosphotyrosine binding
transcription factor activity, sequence-specific DNA binding
ubiquitin-protein transferase activity
signal transducer activity
calcium ion binding
protein binding
zinc ion binding
ligase activity
SH3 domain binding
protein kinase binding
ephrin receptor binding
ubiquitin protein ligase activity
cadherin binding involved in cell-cell adhesion