30259

Gene Symbol:

SMURF2 LOC107984974

Gene Name:

SMAD specific E3 ubiquitin protein ligase 2

uncharacterized LOC107984974

Gene Aliases:

-

-

Chromosome Location:

Chr.17: 64542282 - 64662268 on Build GRCh38

Chromosome Location:

Chr.17: 31005122 - 31034513 on Build GRCh38

UniGene ID:

Hs.515011

-

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: SMURF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022739.3	NP_073576.1	3	510
	XM_005257585.3	XP_005257642.1	2	110
	XM_011525128.1	XP_011523430.1	3	128
GenBank mRNA	AF301463.1	-	3	130
	AF310676.1	-	3	122
	AY014180.1	-	3	310
	BC093876.1	-	3	192	7939721
	BC111945.1	-	3	194	8327413
	BP363931.1	-	4	283
	CB267500.1	-	4	252
	CN310238.1	-	4	238
	CR936721.1	-	3	131

Gene Symbol: LOC107984974
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017025491.1	XP_016880980.1	3	737

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
ubiquitin-dependent protein catabolic process
regulation of transforming growth factor beta receptor signaling pathway
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of transcription, DNA-templated
Wnt signaling pathway, planar cell polarity pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of trophoblast cell migration

Function(s)

ubiquitin-protein transferase activity
transforming growth factor beta receptor binding
protein binding
ligase activity
identical protein binding
SMAD binding
ubiquitin protein ligase activity