3068

• Gene Symbol: KDM5B
• Gene Name: lysine demethylase 5B
• Gene Aliases: CT31, JARID1B, PLU-1, PLU1, PPP1R98, PUT1, RBBP2H1A, RBP2-H1
• Chromosome Location: Chr.1: 202725185 - 202809470 on Build GRCh38
• UniGene ID: Hs.18891
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: KDM5B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001314042.1	NP_001300971.1	4	1617
	NM_006618.4	NP_006609.3	4	1617
	XM_011509088.2	XP_011507390.1	4	669
	XM_011509090.2	XP_011507392.1	4	598
	XM_011509091.2	XP_011507393.1	4	335
	XM_011509092.2	XP_011507394.1	4	560
GenBank mRNA	AF087481.1	-	4	571
	AJ132440.1	-	4	541
	AJ243706.1	-	4	1620
	AK122752.1	-	4	571

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_152895, AY082429, BC048180, AK163481, AK008738, and others.

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
single fertilization
post-embryonic development
positive regulation of gene expression
positive regulation of mammary gland epithelial cell proliferation
histone H3-K4 demethylation
histone H3-K4 demethylation, trimethyl-H3-K4-specific
cellular response to fibroblast growth factor stimulus
negative regulation of transcription, DNA-templated
rhythmic process
oxidation-reduction process
branching involved in mammary gland duct morphogenesis
mammary duct terminal end bud growth
response to fungicide
uterus morphogenesis
lens fiber cell differentiation
regulation of estradiol secretion

Function(s)

DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
zinc ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
histone demethylase activity
histone demethylase activity (H3-K4 specific)
histone demethylase activity (H3-trimethyl-K4 specific)
histone demethylase activity (H3-dimethyl-K4 specific)