3093

• Gene Symbol: ARNT
• Gene Name: aryl hydrocarbon receptor nuclear translocator
• Gene Aliases: HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2
• Chromosome Location: Chr.1: 150809705 - 150876768 on Build GRCh38
• UniGene ID: Hs.632446
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARNT
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001197325.1	NP_001184254.1	2, 3	345
	NM_001286035.1	NP_001272964.1	3, 4	401
	NM_001286036.1	NP_001272965.1	2, 3	345
	NM_001668.3	NP_001659.1	2, 3	345
	NM_178427.2	NP_848514.1	2, 3	345
	XM_005245151.1	XP_005245208.1	2, 3	287
	XM_005245153.1	XP_005245210.1	2, 3	287
	XM_005245154.3	XP_005245211.1	3, 4	315
	XM_005245157.1	XP_005245214.1	2, 3	287
	XM_017001288.1	XP_016856777.1	3, 4	190
	XM_017001289.1	XP_016856778.1	3, 4	190
	XM_017001290.1	XP_016856779.1	3, 4	189
	XM_017001291.1	XP_016856780.1	3, 4	191
	XM_017001292.1	XP_016856781.1	3, 4	191
	XM_017001293.1	XP_016856782.1	3, 4	193
	XM_017001294.1	XP_016856783.1	2, 3	287
	XM_017001295.1	XP_016856784.1	2, 3	287
	XM_017001296.1	XP_016856785.1	2, 3	296
GenBank mRNA	AB209877.1	-	2, 3	156
	AF001307.1	-	2, 3	199
	AK223459.1	-		209
	AK290177.1	-	2, 3	284
	AK291705.1	-	2, 3	187
	AK293027.1	-	2, 3	345
	AK313780.1	-	2, 3	286
	AK315812.1	-	2, 3	184
	AL834279.1	-	3, 4	340
	BC041121.1	-	2, 3	159
	BC060838.1	-	2, 3	280	5300334
	M69238.1	-	2, 3	200

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012780, XM_008761280, XM_008761281, XM_006232850, XM_006232853, and others.
This siRNA also targets the following transcripts in Mouse: NM_001037737, NM_009709, CJ183661, AK028546, U10325, and others.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

response to hypoxia
embryonic placenta development
positive regulation of endothelial cell proliferation
transcription, DNA-templated
positive regulation of vascular endothelial growth factor production
cell differentiation
intracellular receptor signaling pathway
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of protein sumoylation
mRNA transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
positive regulation of erythrocyte differentiation
positive regulation of glycolytic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone biosynthetic process
regulation of transcription from RNA polymerase II promoter in response to hypoxia

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
aryl hydrocarbon receptor activity
protein binding
transcription factor binding
aryl hydrocarbon receptor binding
enhancer binding
sequence-specific DNA binding
protein heterodimerization activity