3105

• Gene Symbol: MSX1
• Gene Name: msh homeobox 1
• Gene Aliases: ECTD3, HOX7, HYD1, STHAG1
• Chromosome Location: Chr.4: 4859665 - 4863936 on Build GRCh38
• UniGene ID: Hs.424414
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MSX1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002448.3	NP_002439.2	2	921
GenBank mRNA	AK290636.1	-	2	922
	BC021285.2	-	2	888	5018103
	BC067353.1	-	2	681	4893288
	M97676.1	-	2	908

More Information

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
in utero embryonic development
epithelial to mesenchymal transition involved in endocardial cushion formation
transcription from RNA polymerase II promoter
muscle organ development
negative regulation of cell proliferation
anterior/posterior pattern specification
mesenchymal cell proliferation
signal transduction involved in regulation of gene expression
negative regulation of cell growth
positive regulation of BMP signaling pathway
forebrain development
midbrain development
protein localization to nucleus
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
embryonic nail plate morphogenesis
middle ear morphogenesis
odontogenesis of dentin-containing tooth
regulation of odontogenesis
negative regulation of apoptotic process
positive regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of transcription from RNA polymerase II promoter
stem cell differentiation
protein stabilization
negative regulation of striated muscle cell differentiation
palate development
face morphogenesis
bone morphogenesis
cartilage morphogenesis
mammary gland epithelium development
BMP signaling pathway involved in heart development
activation of meiosis
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
negative regulation of transcription regulatory region DNA binding
positive regulation of mesenchymal cell apoptotic process

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
p53 binding