314 Validated

• Gene Symbol: PKN1
• Gene Name: protein kinase N1
• Gene Aliases: DBK, PAK-1, PAK1, PKN, PKN-ALPHA, PRK1, PRKCL1
• Chromosome Location: Chr.19: 14433354 - 14471867 on Build GRCh38
• UniGene ID: Hs.466044
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PKN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002741.3	NP_002732.3	4	689
	NM_213560.1	NP_998725.1	4	556
	XM_011528128.1	XP_011526430.1	4	572
GenBank mRNA	AK123007.1	-	4	570
	AK292130.1	-	4	553
	AK313886.1	-	4	529
	BC040061.1	-	4	686	5752583
	BC094766.1	-	4	720	30342125
	D26181.1	-	4	557
	S75546.1	-	4	605
	U33053.1	-	4	605

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001199593, NM_177262, AK149649, AK134792, AK171297, and others.

Matching Taqman Gene Expression Assay:

Hs00177028_m1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

B cell homeostasis
B cell apoptotic process
regulation of germinal center formation
regulation of immunoglobulin production
renal system process
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
activation of JUN kinase activity
epithelial cell migration
peptidyl-serine phosphorylation
negative regulation of B cell proliferation
histone H3-T11 phosphorylation
spleen development
regulation of cell motility

Function(s)

chromatin binding
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein kinase C binding
protein binding
ATP binding
GTP-Rho binding
ligand-dependent nuclear receptor transcription coactivator activity
histone kinase activity (H3-T11 specific)
histone binding
histone deacetylase binding
Rac GTPase binding
androgen receptor binding