3259

• Gene Symbol: GLI3
• Gene Name: GLI family zinc finger 3
• Gene Aliases: ACLS, GCPS, GLI3-190, GLI3FL, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV
• Chromosome Location: Chr.7: 41960949 - 42237019 on Build GRCh38
• UniGene ID: Hs.21509
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GLI3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000168.5	NP_000159.3	15	4999
GenBank mRNA	AK299299.1	-	14	4885
	M57609.1	-	14	4963

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008130, X95255.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
metanephros development
branching involved in ureteric bud morphogenesis
in utero embryonic development
positive regulation of neuroblast proliferation
transcription from RNA polymerase II promoter
smoothened signaling pathway
axon guidance
hindgut morphogenesis
heart development
negative regulation of cell proliferation
anterior/posterior pattern specification
proximal/distal pattern formation
protein processing
optic nerve morphogenesis
hippocampus development
smoothened signaling pathway involved in ventral spinal cord interneuron specification
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
forebrain dorsal/ventral pattern formation
layer formation in cerebral cortex
forebrain radial glial cell differentiation
lateral ganglionic eminence cell proliferation
melanocyte differentiation
lung development
positive regulation of chondrocyte differentiation
T cell differentiation in thymus
limb morphogenesis
wound healing
positive regulation of protein import into nucleus
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
negative regulation of apoptotic process
nose morphogenesis
tongue development
response to estrogen
negative thymic T cell selection
negative regulation of neuron differentiation
positive regulation of osteoblast differentiation
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of alpha-beta T cell differentiation
negative regulation of alpha-beta T cell differentiation
embryonic digestive tract morphogenesis
embryonic digestive tract development
developmental growth
camera-type eye morphogenesis
embryonic skeletal system morphogenesis
oligodendrocyte differentiation
palate development
frontal suture morphogenesis
lambdoid suture morphogenesis
sagittal suture morphogenesis
mammary gland specification
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
artery development
anterior semicircular canal development
lateral semicircular canal development
cell differentiation involved in kidney development
thymocyte apoptotic process
negative regulation of canonical Wnt signaling pathway
regulation of bone development

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
beta-catenin binding
histone acetyltransferase binding
histone deacetylase binding
metal ion binding