3351

• Gene Symbol: TBX5
• Gene Name: T-box 5
• Gene Aliases: HOS
• Chromosome Location: Chr.12: 114353911 - 114408708 on Build GRCh38
• UniGene ID: Hs.381715
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TBX5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000192.3	NP_000183.2	3	831
	NM_080717.2	NP_542448.1	2	646
	NM_181486.2	NP_852259.1	3	738
	XM_017019912.1	XP_016875401.1	3	2582
GenBank mRNA	AB051068.1	-	2	591
	AF221714.1	-	3	829
	AK290611.1	-	3	335
	BC027942.1	-	3	659	5204163
	DA863182.1	-	3	435
	U80987.1	-	2	164
	U89353.1	-	2	164
	Y09445.1	-	3	823

More Information

Panther Classification:

Molecular Function -

Rel homology transcription factor

Gene Ontology Categories:

Process(es)

morphogenesis of an epithelium
bundle of His development
atrioventricular valve morphogenesis
endocardial cushion development
cardiac left ventricle formation
ventricular septum development
transcription initiation from RNA polymerase II promoter
cell-cell signaling
pattern specification process
heart development
negative regulation of cell proliferation
negative regulation of epithelial to mesenchymal transition
lung development
embryonic limb morphogenesis
negative regulation of cell migration
embryonic forelimb morphogenesis
forelimb morphogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of cardioblast differentiation
cardiac muscle cell differentiation
pericardium development
negative regulation of cardiac muscle cell proliferation
positive regulation of cardiac muscle cell proliferation
transdifferentiation
atrial septum morphogenesis
cell migration involved in coronary vasculogenesis
positive regulation of secondary heart field cardioblast proliferation
regulation of execution phase of apoptosis

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
sequence-specific DNA binding