3362

• Gene Symbol: ATF2
• Gene Name: activating transcription factor 2
• Gene Aliases: CRE-BP1, CREB-2, CREB2, HB16, TREB7
• Chromosome Location: Chr.2: 175072250 - 175168206 on Build GRCh38
• UniGene ID: Hs.592510
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ATF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256090.1	NP_001243019.1	6	459
	NM_001256091.1	NP_001243020.1	5	384
	NM_001256094.1	NP_001243023.1	5	424
	NM_001880.3	NP_001871.2	5	424
	NR_045768.1		6	459
	NR_045769.1		6	459
	NR_045770.1		6	459
	NR_045771.1		5	424
	NR_045774.1		5	424
GenBank mRNA	BC026175.1	-	5	391
	BC130335.1	-	4	190	40146366
	BC130337.1	-	4	190	40146368
	DA995464.1	-	5	424
	DQ003036.1	-	6	422
	DQ003037.1	-	5	387
	DQ003039.1	-	5	387
	DQ003041.1	-	6	422
	DQ003043.1	-	6	422
	DQ003044.1	-	6	422
	DQ003047.1	-	5	387
	DQ003049.1	-	5	347
	X15875.1	-	3	151

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031018, U38938, M65148, AY724488.
This siRNA also targets the following transcripts in Mouse: NM_001025093, NM_001284371, NM_001284370, NM_001284372, NM_001284373, and others.

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
outflow tract morphogenesis
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to osmotic stress
cellular response to DNA damage stimulus
response to water deprivation
histone acetylation
intra-S DNA damage checkpoint
positive regulation of transforming growth factor beta2 production
positive regulation of neuron apoptotic process
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of epithelial cell proliferation
regulation of sequence-specific DNA binding transcription factor activity
positive regulation of sequence-specific DNA binding transcription factor activity
adipose tissue development
amelogenesis
positive regulation of mitochondrial membrane permeability involved in apoptotic process

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
cAMP response element binding protein binding
protein kinase binding
cAMP response element binding
metal ion binding
protein heterodimerization activity