359

• Gene Symbol: RYK
• Gene Name: receptor-like tyrosine kinase
• Gene Aliases: D3S3195, JTK5, JTK5A, RYK1
• Chromosome Location: Chr.3: 134157133 - 134250834 on Build GRCh38
• UniGene ID: Hs.654562
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RYK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001005861.2	NP_001005861.1	2, 3	452
	NM_002958.3	NP_002949.2	2, 3	452
GenBank mRNA	CN309980.1	-	2, 3	296
	S59184.1	-	2, 3	485
	X69970.1	-	2, 3	452
	X96588.1	-	3, 4	357

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_080402, XM_008766473, AY669340.
This siRNA also targets the following transcripts in Mouse: NM_013649, NM_001042607, M98547, L02210, L38394, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

protein phosphorylation
signal transduction
axonogenesis
axon guidance
synapse assembly
Wnt signaling pathway
peptidyl-tyrosine phosphorylation
neurogenesis
corpus callosum development
neuron differentiation
neuron projection development
cell proliferation in midbrain
non-canonical Wnt signaling pathway
chemorepulsion of dopaminergic neuron axon
positive regulation of MAPK cascade
canonical Wnt signaling pathway
commissural neuron axon guidance
planar cell polarity pathway involved in axon guidance
midbrain dopaminergic neuron differentiation
Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation

Function(s)

protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
transmembrane signaling receptor activity
frizzled binding
protein binding
ATP binding
Wnt-protein binding
Wnt-activated receptor activity
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway