37184

• Gene Symbol: MAPK8
• Gene Name: mitogen-activated protein kinase 8
• Gene Aliases: JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c
• Chromosome Location: Chr.10: 48306639 - 48439360 on Build GRCh38
• UniGene ID: Hs.138211
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAPK8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001278547.1	NP_001265476.1	6	769
	NM_001278548.1	NP_001265477.1	5	586
	NM_001323302.1	NP_001310231.1	8	1032
	NM_001323320.1	NP_001310249.1	6	769
	NM_001323321.1	NP_001310250.1	6	769
	NM_001323322.1	NP_001310251.1	8	1032
	NM_001323323.1	NP_001310252.1	7	838
	NM_001323324.1	NP_001310253.1	6	769
	NM_001323325.1	NP_001310254.1	7	963
	NM_001323326.1	NP_001310255.1	7	838
	NM_001323327.1	NP_001310256.1	7	963
	NM_001323328.1	NP_001310257.1	7	838
	NM_001323329.1	NP_001310258.1	6	769
	NM_001323330.1	NP_001310259.1	7	963
	NM_001323331.1	NP_001310260.1	7	963
	NM_139046.3	NP_620634.1	8	1032
	NM_139049.3	NP_620637.1	8	1032
	NR_136583.1		6	769
	NR_136584.1		6	769
	NR_136585.1		6	769
GenBank mRNA	AB451231.1	-	5	537
	AB451271.1	-	5	537
	AB451354.1	-	5	537
	AB451398.1	-	5	537
	AK292523.1	-	6	665
	BC130570.1	-	5	599	40146601
	BC130572.1	-	5	599	40146603
	BC144063.1	-	5	599	9052583
	DQ234352.1	-	5	537
	L26318.1	-	5	555
	U34822.1	-	5	549
	U35004.1	-	5	555
	U35005.1	-	5	550

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: L27129, EU253566.
This siRNA also targets the following transcripts in Mouse: NM_016700, AB206575, BC053027, AK030767, AK043102, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

protein phosphorylation
response to stress
JNK cascade
JUN phosphorylation
response to UV
positive regulation of gene expression
regulation of macroautophagy
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
regulation of histone deacetylation
positive regulation of cyclase activity
negative regulation of protein binding
regulation of protein localization
Fc-epsilon receptor signaling pathway
regulation of circadian rhythm
positive regulation of apoptotic process
negative regulation of apoptotic process
rhythmic process
regulation of sequence-specific DNA binding transcription factor activity
positive regulation of protein metabolic process
cellular response to lipopolysaccharide
cellular response to mechanical stimulus
positive regulation of deacetylase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein serine/threonine kinase activity
JUN kinase activity
protein binding
ATP binding
kinase activity
enzyme binding
histone deacetylase regulator activity
histone deacetylase binding