3920

• Gene Symbol: CFTR
• Gene Name: cystic fibrosis transmembrane conductance regulator
• Gene Aliases: ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1
• Chromosome Location: Chr.7: 117478367 - 117668665 on Build GRCh38
• UniGene ID: Hs.489786
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CFTR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000492.3	NP_000483.3	2	214
	XM_011515751.2	XP_011514053.1	3	187
	XM_011515753.1	XP_011514055.1	3	304
	XM_011515754.2	XP_011514056.1	4	1205
	XM_017011699.1	XP_016867188.1	3	951
GenBank mRNA	M28668.1	-	2	214

More Information

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter

Gene Ontology Categories:

Process(es)

cholesterol biosynthetic process
transport
vesicle docking involved in exocytosis
respiratory gaseous exchange
bicarbonate transport
cholesterol transport
positive regulation of insulin secretion involved in cellular response to glucose stimulus
positive regulation of exocytosis
sperm capacitation
intracellular pH elevation
transmembrane transport
membrane hyperpolarization
cellular response to cAMP
positive regulation of cyclic nucleotide-gated ion channel activity
chloride transmembrane transport
positive regulation of voltage-gated chloride channel activity

Function(s)

ATP-binding and phosphorylation-dependent chloride channel activity
chloride channel activity
channel-conductance-controlling ATPase activity
protein binding
ATP binding
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
chloride channel regulator activity
chloride channel inhibitor activity
enzyme binding
PDZ domain binding
anion transmembrane-transporting ATPase activity