3934

• Gene Symbol: RARA
• Gene Name: retinoic acid receptor alpha
• Gene Aliases: NR1B1, RAR
• Chromosome Location: Chr.17: 40309171 - 40357643 on Build GRCh38
• UniGene ID: Hs.654583
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RARA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000964.3	NP_000955.1	9	2457
	NM_001024809.3	NP_001019980.1	8	2650
	NM_001145301.2	NP_001138773.1	9	2569
	NM_001145302.2	NP_001138774.1	7	2278
	XM_005257552.4	XP_005257609.1	8	2027
	XM_005257553.1	XP_005257610.1	9	2361
	XM_005257554.1	XP_005257611.1	9	2610
	XM_011525095.1	XP_011523397.1	10	2507
	XM_011525096.1	XP_011523398.1	8	1820
	XM_017024920.1	XP_016880409.1	8	1929
GenBank mRNA	AK130192.1	-	9	2493
	FJ487576.1	-	7	2214
	X06614.1	-	8	2081

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008767945.
This siRNA also targets the following transcripts in Mouse: NM_001177303, NM_001176528, NM_001177302, NM_009024, BC040383, and others.

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ureteric bud development
neural tube closure
liver development
glandular epithelial cell development
outflow tract septum morphogenesis
growth plate cartilage development
transcription initiation from RNA polymerase II promoter
protein phosphorylation
signal transduction
germ cell development
spermatogenesis
female pregnancy
positive regulation of cell proliferation
negative regulation of cell proliferation
hippocampus development
prostate gland development
negative regulation of granulocyte differentiation
embryonic camera-type eye development
regulation of myelination
response to estradiol
response to retinoic acid
negative regulation of interferon-gamma production
negative regulation of tumor necrosis factor production
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-5 production
response to vitamin A
response to cytokine
multicellular organism growth
negative regulation of apoptotic process
apoptotic cell clearance
steroid hormone mediated signaling pathway
response to ethanol
positive regulation of T-helper 2 cell differentiation
positive regulation of neuron differentiation
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of translational initiation
regulation of synaptic plasticity
retinoic acid receptor signaling pathway
positive regulation of binding
ventricular cardiac muscle cell differentiation
Sertoli cell fate commitment
limb development
face development
trachea cartilage development
chondroblast differentiation
negative regulation of cartilage development
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to estrogen stimulus

Function(s)

translation repressor activity, nucleic acid binding
RNA polymerase II regulatory region sequence-specific DNA binding
retinoic acid binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
retinoic acid receptor activity
transcription coactivator activity
transcription corepressor activity
receptor binding
protein binding
transcription factor binding
drug binding
zinc ion binding
enzyme binding
protein domain specific binding
chromatin DNA binding
histone deacetylase binding
protein kinase B binding
retinoic acid-responsive element binding
protein heterodimerization activity
mRNA 5'-UTR binding
protein kinase A binding
alpha-actinin binding