39729

• Gene Symbol: PYDC1
• Gene Name: pyrin domain containing 1
• Gene Aliases: ASC2, POP1, PYC1, cPOP1
• Chromosome Location: Chr.16: 31215962 - 31217093 on Build GRCh38
• UniGene ID: Hs.58314
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PYDC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_152901.3	NP_690865.1	2	372
GenBank mRNA	AF086332.1	-	2	372
	AF454669.1	-	2	361
	AF467809.1	-	2	367
	AY163727.1	-	2	372
	BC105033.1	-	2	358	8144036
	BC105035.1	-	2	358	8144038

More Information

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

activation of innate immune response
positive regulation of defense response to virus by host
myeloid dendritic cell activation involved in immune response
positive regulation of antigen processing and presentation of peptide antigen via MHC class II
negative regulation of protein kinase activity
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
response to bacterium
regulation of autophagy
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of actin filament polymerization
regulation of protein stability
negative regulation of NF-kappaB transcription factor activity
interleukin-1 beta production
positive regulation of interferon-gamma production
positive regulation of interleukin-6 production
tumor necrosis factor-mediated signaling pathway
positive regulation of activated T cell proliferation
regulation of GTPase activity
macropinocytosis
innate immune response
negative regulation of interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
regulation of inflammatory response
positive regulation of phagocytosis
positive regulation of ERK1 and ERK2 cascade
positive regulation of chemokine secretion
activation of cysteine-type endopeptidase activity
negative regulation of NLRP3 inflammasome complex assembly
positive regulation of T cell migration

Function(s)

protein binding
protein dimerization activity