40758

• Gene Symbol: ATP2A1
• Gene Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
• Gene Aliases: ATP2A, SERCA1
• Chromosome Location: Chr.16: 28878488 - 28904509 on Build GRCh38
• UniGene ID: Hs.657344
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ATP2A1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001286075.1	NP_001273004.1	8, 9	1023
	NM_004320.4	NP_004311.1	10, 11	1374
	NM_173201.3	NP_775293.1	10, 11	1374
GenBank mRNA	AK128456.1	-	8, 9	1013
	AK291314.1	-	10, 11	1303
	BC037354.1	-	10, 11	1302
	BX537389.1	-	10, 11	1370
	BX647365.1	-	10, 11	1370
	BX647366.1	-	10, 11	1366
	BX647367.1	-	10, 11	1374
	BX647368.1	-	3, 4	412
	BX648544.1	-	10, 11	1371
	BX649072.1	-	10, 11	1363

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_007504, BC036292, AY081946.

Panther Classification:

Molecular Function -

primary active transporter

Gene Ontology Categories:

Process(es)

calcium ion transport
apoptotic mitochondrial changes
positive regulation of fast-twitch skeletal muscle fiber contraction
positive regulation of endoplasmic reticulum calcium ion concentration
negative regulation of endoplasmic reticulum calcium ion concentration
ion transmembrane transport
response to endoplasmic reticulum stress
positive regulation of mitochondrial calcium ion concentration
maintenance of mitochondrion location
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
calcium ion import
calcium ion transmembrane transport
relaxation of skeletal muscle
regulation of cardiac conduction

Function(s)

calcium-transporting ATPase activity
calcium ion binding
protein binding
ATP binding
protein homodimerization activity