4095

• Gene Symbol: FAS
• Gene Name: Fas cell surface death receptor
• Gene Aliases: ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6
• Chromosome Location: Chr.10: 88968429 - 89017061 on Build GRCh38
• UniGene ID: Hs.244139
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FAS
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000043.5	NP_000034.1	9	2036
	NM_001320619.1	NP_001307548.1	8	1953
	NM_152871.3	NP_690610.1	8	1973
	NM_152872.3	NP_690611.1	8	2011
	NR_028033.3		7	1864
	NR_028034.3		6	1726
	NR_028035.3		7	1789
	NR_028036.3		8	1927
	NR_135313.1		7	1844
	NR_135314.1		9	2027
	NR_135315.1		7	1780
	XM_006717819.3	XP_006717882.1	10	6718
	XM_011539764.2	XP_011538066.1	10	2107
	XM_011539765.2	XP_011538067.1	9	1832
	XM_011539766.2	XP_011538068.1	10	1847
	XM_011539767.2	XP_011538069.1	9	1770
GenBank mRNA	AB209361.1	-	10	5353
	BC012479.1	-	9	2028	4514272
	M67454.1	-	9	1912
	X63717.1	-	9	1938

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

ovarian follicle atresia
immunoglobulin production
renal system process
protein complex assembly
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
activation-induced cell death of T cells
inflammatory cell apoptotic process
inflammatory response
immune response
signal transduction
spermatogenesis
brain development
aging
circadian rhythm
extrinsic apoptotic signaling pathway via death domain receptors
response to toxic substance
gene expression
regulation of gene expression
B cell mediated immunity
telencephalon development
dendrite regeneration
positive regulation of protein homooligomerization
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
response to drug
ovulation cycle
regulation of apoptotic process
chordate embryonic development
positive regulation of apoptotic process
negative regulation of apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MAPK cascade
response to peptide hormone
negative thymic T cell selection
regulation of lymphocyte differentiation
regulation of myeloid cell differentiation
response to cycloheximide
spleen development
negative regulation of B cell activation
protein homooligomerization
response to glucocorticoid
maternal process involved in female pregnancy
positive regulation of lymphocyte apoptotic process
cellular response to hydrogen peroxide
response to growth factor
cellular response to phenylalanine
cellular response to mechanical stimulus
cellular response to cobalt ion
cellular response to lithium ion
cellular response to glucose stimulus
cellular response to interleukin-1
cellular response to estrogen stimulus
cellular response to hyperoxia
cellular response to hypoxia
cellular response to hydrostatic pressure
motor neuron apoptotic process
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
hepatocyte apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
liver regeneration
necroptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
response to fluoride
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

protease binding
signal transducer activity
receptor activity
tumor necrosis factor-activated receptor activity
protein binding
kinase binding
protein complex binding
identical protein binding