41696

• Gene Symbol: GBA
• Gene Name: glucosylceramidase beta
• Gene Aliases: GBA1, GCB, GLUC
• Chromosome Location: Chr.1: 155234448 - 155244862 on Build GRCh38
• UniGene ID: Hs.282997
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GBA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000157.3	NP_000148.2	4	505
	NM_001005741.2	NP_001005741.1	5	764
	NM_001005742.2	NP_001005742.1	5	745
	NM_001171811.1	NP_001165282.1	3	581
GenBank mRNA	AK291911.1	-	5	743
	AK300829.1	-	3	418
	AK300876.1	-	5	745
	AK302000.1	-	3	330
	AK311242.1	-	5	353
	AK312502.1	-	5	561
	AL547558.3	-	6	676
	AU122729.1	-	6	665
	AU131071.1	-	5	573
	AU140959.1	-	4	489
	AU141794.1	-	5	580
	BC003356.1	-	4	444	2899915
	BI458641.1	-	5	706
	BX382279.2	-	6	663
	D13286.1	-	4	444
	DC297079.1	-	4	505
	K02920.1	-	3	324
	KJ690771.1	-	4	388
	KJ690772.1	-	4	388
	KJ690773.1	-	4	388
	M16328.1	-	4	774
	M19285.1	-	4	461

More Information

Gene Ontology Categories:

Process(es)

carbohydrate metabolic process
glucosylceramide catabolic process
glycosphingolipid metabolic process
cellular response to starvation
response to pH
positive regulation of macroautophagy
regulation of macroautophagy
termination of signal transduction
regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of interleukin-6 production
regulation of water loss via skin
response to testosterone
positive regulation of protein dephosphorylation
negative regulation of MAP kinase activity
skin morphogenesis
response to estrogen
sphingosine biosynthetic process
ceramide biosynthetic process
negative regulation of inflammatory response
response to glucocorticoid
cellular response to tumor necrosis factor
response to thyroid hormone
positive regulation of proteolysis involved in cellular protein catabolic process

Function(s)

glucosylceramidase activity
receptor binding
protein binding