41765

• Gene Symbol: NKX2-2
• Gene Name: NK2 homeobox 2
• Gene Aliases: NKX2.2, NKX2B
• Chromosome Location: Chr.20: 21511010 - 21514026 on Build GRCh38
• UniGene ID: Hs.516922
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NKX2-2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002509.3	NP_002500.1	2	932
	XM_006723566.3	XP_006723629.1	2	589
GenBank mRNA	BC075092.2	-	2	603	30915603
	BC075093.2	-	2	603	30915391

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191904.
This siRNA also targets the following transcripts in Mouse: NM_010919, AK141002, U31566, BC138159, BC138160.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

type B pancreatic cell development
pancreatic A cell fate commitment
type B pancreatic cell fate commitment
pancreatic PP cell fate commitment
transcription, DNA-templated
smoothened signaling pathway
brain development
response to glucose
oligodendrocyte development
spinal cord motor neuron differentiation
spinal cord oligodendrocyte cell fate specification
optic nerve development
endocrine pancreas development
response to progesterone
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
neuron fate specification
astrocyte differentiation
positive regulation of oligodendrocyte differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
ventral spinal cord interneuron fate determination

Function(s)

core promoter proximal region DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
transcription factor binding
sequence-specific DNA binding