4196

• Gene Symbol: GRB2
• Gene Name: growth factor receptor bound protein 2
• Gene Aliases: ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
• Chromosome Location: Chr.17: 75318076 - 75405709 on Build GRCh38
• UniGene ID: Hs.444356
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GRB2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002086.4	NP_002077.1	2, 3	443
	NM_203506.2	NP_987102.1	2, 3	444
GenBank mRNA	AF498925.1	-	1, 2	86
	AK091010.1	-	2, 3	871
	AK315565.1	-	2, 3	439
	BC000631.2	-	2, 3	388	3345524
	BI459414.1	-	2, 3	450
	CR450363.1	-	1, 2	86
	CR541942.1	-	1, 2	86
	DA458680.1	-	2, 3	444
	L29511.1	-	1, 2	122
	M96995.1	-	1, 2	164

More Information

Gene Ontology Categories:

Process(es)

MAPK cascade
epidermal growth factor receptor signaling pathway
Ras protein signal transduction
cell-cell signaling
axon guidance
insulin receptor signaling pathway
fibroblast growth factor receptor signaling pathway
positive regulation of signal transduction
regulation of phosphatidylinositol 3-kinase signaling
viral process
positive regulation of actin filament polymerization
T cell costimulation
receptor internalization
phosphatidylinositol-3-phosphate biosynthetic process
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
ERBB2 signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway
signal transduction in response to DNA damage
regulation of MAPK cascade
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
anatomical structure formation involved in morphogenesis
leukocyte migration
branching involved in labyrinthine layer morphogenesis
cellular response to ionizing radiation
positive regulation of reactive oxygen species metabolic process

Function(s)

SH3/SH2 adaptor activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
SH3 domain binding
protein kinase binding
protein phosphatase binding
identical protein binding
insulin receptor substrate binding
poly(A) RNA binding
ephrin receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity