41977

• Gene Symbol: SOCS3
• Gene Name: suppressor of cytokine signaling 3
• Gene Aliases: ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3
• Chromosome Location: Chr.17: 78356777 - 78360079 on Build GRCh38
• UniGene ID: Hs.527973
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SOCS3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003955.4	NP_003946.3	2	699
GenBank mRNA	AB004904.1	-	1	387
	AB006967.1	-	1	281
	AF159854.1	-	1	281
	AK309756.1	-	3	465
	AK314212.1	-	2	697
	BC060858.1	-	2	697	30333577
	BT019544.1	-	1	281
	CR536497.1	-	1	281
	CR541694.1	-	1	281

More Information

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

response to hypoxia
negative regulation of protein kinase activity
JAK-STAT cascade
aging
response to heat
response to gamma radiation
protein ubiquitination
cytokine-mediated signaling pathway
organ regeneration
response to food
response to estradiol
response to lipopolysaccharide
response to progesterone
response to insulin
regulation of growth
response to drug
negative regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of apoptotic process
positive regulation of cell differentiation
negative regulation of JAK-STAT cascade
negative regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
response to glucocorticoid
regulation of interferon-gamma-mediated signaling pathway
branching involved in labyrinthine layer morphogenesis
placenta blood vessel development
trophoblast giant cell differentiation
spongiotrophoblast differentiation

Function(s)

protein kinase inhibitor activity
protein binding