42159

• Gene Symbol: NR1H2
• Gene Name: nuclear receptor subfamily 1 group H member 2
• Gene Aliases: LXR-b, LXRB, NER, NER-I, RIP15, UNR
• Chromosome Location: Chr.19: 50376423 - 50383028 on Build GRCh38
• UniGene ID: Hs.432976
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NR1H2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007121.5	NP_009052.3	5, 6	757
GenBank mRNA	AB307697.1	-	3, 4	476
	AK290855.1	-	5, 6	688
	BC007790.1	-	5, 6	624	3636961
	BC033500.1	-	5, 6	675	5178510
	BC047750.2	-	5, 6	711	6469687
	BC074500.1	-	5, 6	692	5211737
	CR456706.1	-	3, 4	476
	CR749648.1	-	5, 6	707
	HQ692835.1	-	3, 4	476
	U07132.1	-	5, 6	720
	U14534.1	-	3, 4	458

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
negative regulation of macrophage derived foam cell differentiation
positive regulation of triglyceride biosynthetic process
positive regulation of cholesterol efflux
positive regulation of lipid storage
negative regulation of cholesterol storage
positive regulation of cellular protein metabolic process
negative regulation of lipid transport
positive regulation of cholesterol transport
cholesterol homeostasis
steroid hormone mediated signaling pathway
cellular lipid metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
negative regulation of pinocytosis
positive regulation of lipoprotein lipase activity
negative regulation of interferon-gamma-mediated signaling pathway
positive regulation of high-density lipoprotein particle assembly
positive regulation of pancreatic juice secretion
positive regulation of secretion of lysosomal enzymes
regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding
DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
apolipoprotein A-I receptor binding
retinoid X receptor binding
ATPase binding