4256

• Gene Symbol: PPP2CA
• Gene Name: protein phosphatase 2 catalytic subunit alpha
• Gene Aliases: PP2Ac, PP2CA, PP2Calpha, RP-C
• Chromosome Location: Chr.5: 134196457 - 134226259 on Build GRCh38
• UniGene ID: Hs.105818
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PPP2CA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002715.2	NP_002706.1	1, 2	508
GenBank mRNA	AB451240.1	-	1, 2	110
	AB451365.1	-	1, 2	110
	AK097599.1	-	1, 2	320
	BC000400.2	-	1, 2	309	2822635
	BC002657.2	-	1, 2	309	3607862
	BC019275.1	-	1, 2	309	2822635
	BC031696.1	-	1, 2	309	5001649
	CR457417.1	-	1, 2	110
	J03804.1	-	1, 2	292
	X12646.1	-	1, 2	193

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017039, XM_008773894, BC070914, X14159, BC072531, and others.
This siRNA also targets the following transcripts in Mouse: NM_019411, AK172644, AF076192, BC003856, AK076110, and others.

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
inactivation of MAPK activity
regulation of DNA replication
regulation of transcription, DNA-templated
protein dephosphorylation
ceramide metabolic process
apoptotic process
mitotic nuclear envelope reassembly
mesoderm development
RNA splicing
response to organic substance
negative regulation of epithelial to mesenchymal transition
second-messenger-mediated signaling
regulation of Wnt signaling pathway
regulation of cell adhesion
negative regulation of cell growth
regulation of growth
negative regulation of tyrosine phosphorylation of Stat3 protein
regulation of cell differentiation
meiotic cell cycle
positive regulation of protein serine/threonine kinase activity

Function(s)

phosphoprotein phosphatase activity
protein binding
protein C-terminus binding
metal ion binding
GABA receptor binding