42709

• Gene Symbol: PML
• Gene Name: promyelocytic leukemia
• Gene Aliases: MYL, PP8675, RNF71, TRIM19
• Chromosome Location: Chr.15: 73994673 - 74047819 on Build GRCh38
• UniGene ID: Hs.526464
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PML
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002675.3	NP_002666.1	2	697
	NM_033238.2	NP_150241.2	2	697
	NM_033239.2	NP_150242.1	2	697
	NM_033240.2	NP_150243.2	2	697
	NM_033244.3	NP_150247.2	2	697
	NM_033246.2	NP_150249.1	2	697
	NM_033247.2	NP_150250.2	2	697
	NM_033249.2	NP_150252.1	2	697
	NM_033250.2	NP_150253.2	2	697
GenBank mRNA	AB208950.1	-	2	567
	AB209051.1	-	1	408
	AB209411.1	-	2	641
	AF230401.1	-	2	629
	AF230402.1	-	2	629
	AF230403.1	-	2	629
	AF230404.1	-	2	629
	AF230405.1	-	2	629
	AF230406.1	-	2	629
	AF230407.1	-	2	629
	AF230408.1	-	2	629
	AF230409.1	-	2	629
	AF230410.1	-	2	629
	AF230411.1	-	2	629
	BC000080.2	-	2	618	3506984
	BC020994.2	-	2	618	2958462
	BT009911.1	-	2	557
	M73778.1	-	2	637
	M79462.1	-	2	571
	M79463.1	-	2	571
	M79464.1	-	2	571
	M80185.1	-	2	571
	S50913.1	-	2	639
	X63131.1	-	2	698

More Information

Gene Ontology Categories:

Process(es)

response to hypoxia
regulation of protein phosphorylation
transcription, DNA-templated
regulation of transcription, DNA-templated
protein complex assembly
activation of cysteine-type endopeptidase activity involved in apoptotic process
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
cell cycle arrest
transforming growth factor beta receptor signaling pathway
common-partner SMAD protein phosphorylation
SMAD protein import into nucleus
negative regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to oxidative stress
response to UV
response to gamma radiation
regulation of calcium ion transport into cytosol
fibroblast migration
negative regulation of angiogenesis
protein sumoylation
myeloid cell differentiation
regulation of cell adhesion
negative regulation of cell growth
PML body organization
positive regulation of telomere maintenance
endoplasmic reticulum calcium ion homeostasis
circadian regulation of gene expression
response to cytokine
regulation of circadian rhythm
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
innate immune response
cell fate commitment
regulation of MHC class I biosynthetic process
negative regulation of transcription, DNA-templated
positive regulation of fibroblast proliferation
retinoic acid receptor signaling pathway
negative regulation of interleukin-1 beta secretion
maintenance of protein location in nucleus
defense response to virus
interferon-gamma-mediated signaling pathway
branching involved in mammary gland duct morphogenesis
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to interleukin-4
cellular senescence
extrinsic apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
negative regulation of viral release from host cell
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
regulation of double-strand break repair
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

DNA binding
protein binding
zinc ion binding
ubiquitin protein ligase binding
SUMO binding
protein homodimerization activity
SMAD binding