42841

• Gene Symbol: JAK1
• Gene Name: Janus kinase 1
• Gene Aliases: JAK1A, JAK1B, JTK3
• Chromosome Location: Chr.1: 64833223 - 65067746 on Build GRCh38
• UniGene ID: Hs.207538
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: JAK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001320923.1	NP_001307852.1	7, 8	864
	NM_001321852.1	NP_001308781.1	6, 7	867
	NM_001321853.1	NP_001308782.1	8, 9	1126
	NM_001321854.1	NP_001308783.1	7, 8	1042
	NM_001321855.1	NP_001308784.1	7, 8	1045
	NM_001321856.1	NP_001308785.1	6, 7	780
	NM_001321857.1	NP_001308786.1	6, 7	961
	NM_002227.3	NP_002218.2	6, 7	961
	XM_017001212.1	XP_016856701.1	6, 7	808
GenBank mRNA	AB209057.1	-	5, 6	717
	AB219242.1	-	4, 5	611
	AK314257.1	-	7, 8	866
	BC009079.1	-	6, 7	896
	BC023604.2	-	4, 5	652
	BC062431.1	-	6, 7	896
	BC111401.1	-	6, 7	926
	BC132729.1	-	5, 6	679	40146751
	HQ628631.1	-	4, 5	641
	M64174.1	-	5, 6	686

More Information

Gene Ontology Categories:

Process(es)

MAPK cascade
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
cell migration
cell differentiation
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
interleukin-2-mediated signaling pathway
regulation of cell proliferation
positive regulation of GTPase activity
innate immune response
response to antibiotic
interferon-gamma-mediated signaling pathway
regulation of interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
regulation of type I interferon-mediated signaling pathway
positive regulation of sprouting angiogenesis

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
protein binding
ATP binding
protein phosphatase binding
ubiquitin protein ligase binding
CCR5 chemokine receptor binding
metal ion binding