4302

• Gene Symbol: IRF8
• Gene Name: interferon regulatory factor 8
• Gene Aliases: H-ICSBP, ICSBP, ICSBP1, IMD32A, IMD32B, IRF-8
• Chromosome Location: Chr.16: 85899168 - 85922606 on Build GRCh38
• UniGene ID: Hs.137427
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IRF8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002163.2	NP_002154.1	2	215
	XM_017023199.1	XP_016878688.1	1	150
GenBank mRNA	AK313524.1	-	2	580
	BC126247.1	-	2	210	8991963
	BG107396.1	-	2	197
	BI835080.1	-	2	214
	M91196.1	-	2	205

More Information

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
phagocytosis
immune response
myeloid cell differentiation
positive regulation of interferon-gamma production
positive regulation of interleukin-12 production
defense response to bacterium
defense response to protozoan
negative regulation of growth of symbiont in host
positive regulation of transcription initiation from RNA polymerase II promoter
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
cellular response to lipopolysaccharide

Function(s)

regulatory region DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding