43437

• Gene Symbol: HHEX
• Gene Name: hematopoietically expressed homeobox
• Gene Aliases: HEX, HMPH, HOX11L-PEN, PRH, PRHX
• Chromosome Location: Chr.10: 92689924 - 92695651 on Build GRCh38
• UniGene ID: Hs.118651
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HHEX
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002729.4	NP_002720.1	2	466
GenBank mRNA	AK309463.1	-	2	1233
	AK314891.1	-	2	435
	BC014336.1	-	2	439	4046641
	BC015110.1	-	2	439	4048691
	BC050638.1	-	2	406	6174612
	DB504532.1	-	2	466
	L16499.1	-	2	438
	X67235.1	-	2	410
	Z21533.1	-	1	381

More Information

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
in utero embryonic development
myeloid leukocyte differentiation
transcription, DNA-templated
mRNA export from nucleus
Notch signaling pathway
endoderm development
cell proliferation
anterior/posterior pattern specification
negative regulation of transcription by transcription factor localization
negative regulation of transcription by competitive promoter binding
Wnt signaling pathway
negative regulation of angiogenesis
poly(A)+ mRNA export from nucleus
interkinetic nuclear migration
cell differentiation
positive regulation of Wnt signaling pathway
B cell differentiation
thyroid gland development
negative regulation of vascular endothelial growth factor receptor signaling pathway
pancreas development
protein localization to nucleus
embryonic heart tube development
multicellular organism growth
regulation of cell proliferation
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
forebrain morphogenesis
primary lung bud formation
gall bladder development
hepatic duct development
hepatoblast differentiation
hepatocyte differentiation
DNA conformation change
primitive streak formation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
protein binding
transcription factor binding
eukaryotic initiation factor 4E binding
DNA binding, bending
TBP-class protein binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
repressing transcription factor binding
HMG box domain binding