43535

• Gene Symbol: IRS2
• Gene Name: insulin receptor substrate 2
• Gene Aliases: IRS-2
• Chromosome Location: Chr.13: 109753837 - 109786567 on Build GRCh38
• UniGene ID: Hs.442344
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IRS2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003749.2	NP_003740.2	1	3276
GenBank mRNA	AF073310.1	-	1	3278

More Information

Gene Ontology Categories:

Process(es)

MAPK cascade
positive regulation of mesenchymal cell proliferation
negative regulation of B cell apoptotic process
glucose metabolic process
signal transduction
brain development
cell proliferation
positive regulation of cell proliferation
insulin receptor signaling pathway
response to glucose
negative regulation of plasma membrane long-chain fatty acid transport
positive regulation of glucose metabolic process
regulation of phosphatidylinositol 3-kinase signaling
regulation of lipid metabolic process
positive regulation of cell migration
mammary gland development
positive regulation of B cell proliferation
positive regulation of fatty acid beta-oxidation
positive regulation of insulin secretion
cellular response to insulin stimulus
negative regulation of kinase activity
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of GTPase activity
positive regulation of glycogen biosynthetic process
positive regulation of glucose import
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
lipid homeostasis
cellular response to glucose stimulus

Function(s)

signal transducer activity
Ras guanyl-nucleotide exchange factor activity
insulin receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
protein kinase binding
protein phosphatase binding
protein domain specific binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
14-3-3 protein binding