4423

Gene Symbol:

PBX2 AGER

Gene Name:

PBX homeobox 2

advanced glycosylation end product-specific receptor

Gene Aliases:

G17, HOX12, PBX2MHC

RAGE, SCARJ1

Chromosome Location:

Chr.6: 32184733 - 32190186 on Build GRCh38

Chromosome Location:

Chr.6: 32180968 - 32185247 on Build GRCh38

UniGene ID:

Hs.509545

Hs.534342

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: PBX2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002586.4	NP_002577.2	9	2804
GenBank mRNA	DB162975.1	-	1	404
	X59842.1	-	9	2827

Gene Symbol: AGER
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017010328.1	XP_016865817.1	1	106

More Information

Panther Classification:

Molecular Function -

homeodomain transcription factor, cell adhesion molecule, immunoglobulin superfamily cell adhesion molecule

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
proximal/distal pattern formation
embryonic limb morphogenesis
positive regulation of transcription from RNA polymerase II promoter
regulation of T cell mediated cytotoxicity
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
negative regulation of endothelial cell proliferation
inflammatory response
negative regulation of cell adhesion
cell surface receptor signaling pathway
JAK-STAT cascade
brain development
glycoprotein metabolic process
response to wounding
response to fructose
positive regulation of autophagy
negative regulation of endothelial cell migration
positive regulation of gene expression
positive regulation of epithelial to mesenchymal transition
positive regulation of fibroblast migration
response to activity
positive regulation of smooth muscle cell migration
lung development
neuron projection development
negative regulation of interleukin-10 production
positive regulation of interleukin-12 production
negative regulation of collagen biosynthetic process
response to vitamin A
response to genistein
negative regulation of osteoblast proliferation
cellular response to drug
positive regulation of activated T cell proliferation
positive regulation of neuron apoptotic process
innate immune response
positive regulation of fibroblast proliferation
positive regulation of smooth muscle cell proliferation
positive regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
response to methylglyoxal
calcium ion homeostasis
response to hyperoxia
positive regulation of phagocytosis, engulfment
transdifferentiation
cellular response to hydrogen peroxide
cellular response to glucose stimulus
cellular response to fatty acid
cellular response to organic cyclic compound
response to selenite ion
positive regulation of potassium ion transmembrane transporter activity
positive regulation of endothelial cell apoptotic process
positive regulation of reactive oxygen species metabolic process
regulation of CD4-positive, alpha-beta T cell activation
positive regulation of type B pancreatic cell apoptotic process
positive regulation of dendritic cell differentiation

Function(s)

chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
sequence-specific DNA binding
receptor activity
transmembrane signaling receptor activity
identical protein binding
S100 protein binding
advanced glycation end-product receptor activity
high mobility group box 1 binding