44845

• Gene Symbol: CCL2
• Gene Name: C-C motif chemokine ligand 2
• Gene Aliases: GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF
• Chromosome Location: Chr.17: 34255277 - 34257203 on Build GRCh38
• UniGene ID: Hs.303649
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CCL2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002982.3	NP_002973.1	1, 2	153
GenBank mRNA	AK311960.1	-	1, 2	145
	AV733621.2	-	1, 2	153
	BC009716.1	-	1, 2	136	3901489
	BG530064.1	-	1, 2	168
	BT007329.1	-	1, 2	80
	M24545.1	-	1, 2	149
	M28226.1	-	1, 2	126
	S69738.1	-	1, 2	111
	S71513.1	-	1, 2	133
	X14768.1	-	1, 2	133

More Information

Panther Classification:

Molecular Function -

cytokine, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
angiogenesis
response to hypoxia
positive regulation of leukocyte mediated cytotoxicity
positive regulation of endothelial cell proliferation
leukocyte migration involved in inflammatory response
monocyte chemotaxis
positive regulation of cellular extravasation
protein phosphorylation
cellular calcium ion homeostasis
chemotaxis
inflammatory response
humoral immune response
cytoskeleton organization
cell adhesion
signal transduction
cell surface receptor signaling pathway
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
JAK-STAT cascade
aging
regulation of cell shape
response to heat
response to wounding
response to mechanical stimulus
response to bacterium
organ morphogenesis
response to gamma radiation
regulation of vascular endothelial growth factor production
positive regulation of macrophage chemotaxis
response to activity
negative regulation of angiogenesis
viral genome replication
cytokine-mediated signaling pathway
cellular homeostasis
neutrophil chemotaxis
organ regeneration
lipopolysaccharide-mediated signaling pathway
response to progesterone
positive regulation of tumor necrosis factor production
cellular response to insulin stimulus
positive regulation of collagen biosynthetic process
response to vitamin B3
negative regulation of glial cell apoptotic process
helper T cell extravasation
cellular response to drug
cellular response to macrophage colony-stimulating factor stimulus
cellular response to platelet-derived growth factor stimulus
PERK-mediated unfolded protein response
response to amino acid
protein kinase B signaling
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
astrocyte cell migration
cellular response to fibroblast growth factor stimulus
response to ethanol
response to antibiotic
vascular endothelial growth factor receptor signaling pathway
macrophage chemotaxis
lymphocyte chemotaxis
positive regulation of inflammatory response
positive regulation of synaptic transmission
positive regulation of T cell activation
positive regulation of nitric-oxide synthase biosynthetic process
maternal process involved in female pregnancy
maternal process involved in parturition
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to ATP
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to interleukin-6
cellular response to tumor necrosis factor
cellular response to high density lipoprotein particle stimulus
cellular response to organic cyclic compound
cellular response to dexamethasone stimulus
positive regulation of monocyte chemotaxis
positive regulation of immune complex clearance by monocytes and macrophages
positive regulation of calcium ion import
positive regulation of protein targeting to membrane
positive regulation of apoptotic cell clearance
negative regulation of natural killer cell chemotaxis

Function(s)

protein kinase activity
receptor binding
chemokine activity
heparin binding
CCR2 chemokine receptor binding