44945

• Gene Symbol: TOP1
• Gene Name: topoisomerase (DNA) I
• Gene Aliases: TOPI
• Chromosome Location: Chr.20: 41028822 - 41124487 on Build GRCh38
• UniGene ID: Hs.472737
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TOP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003286.2	NP_003277.1	3	330
GenBank mRNA	AK225095.1	-	3	329
	AK292943.1	-	3	329
	BC004475.2	-	3	312
	BC039009.1	-	3	329
	BC067349.1	-	3	309
	BC136297.1	-	3	181	9020284
	J03250.1	-	3	295
	U07804.1	-	3	74
	U07806.1	-	3	74

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022615, XM_008759598, AY325188, AF140782.
This siRNA also targets the following transcripts in Mouse: NM_009408, D10061, AK160590, BC048743, BC092349, and others.

Panther Classification:

Molecular Function -

DNA topoisomerase

Gene Ontology Categories:

Process(es)

DNA replication
DNA topological change
chromatin remodeling
chromosome segregation
circadian rhythm
programmed cell death
viral process
phosphorylation
protein sumoylation
circadian regulation of gene expression
embryonic cleavage
response to drug

Function(s)

core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein binding
poly(A) RNA binding