45010

• Gene Symbol: PFN1
• Gene Name: profilin 1
• Gene Aliases: ALS18
• Chromosome Location: Chr.17: 4945650 - 4949088 on Build GRCh38
• UniGene ID: Hs.494691
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PFN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005022.3	NP_005013.1	2	863
	XM_017024761.1	XP_016880250.1	2	865
GenBank mRNA	AK312168.1	-	2	309
	AL525538.3	-	2	739
	BC002475.2	-	2	293	3349355
	BC006768.1	-	2	286	2900010
	BC013439.1	-	2	286	3896948
	BC015164.1	-	2	301	3890384
	BC057828.1	-	2	312	30337970
	BT007001.1	-	2	171
	CR407670.1	-	2	171
	GU727630.1	-	2	171
	J03191.1	-	2	298

More Information

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein, cytoskeletal protein, non-motor actin binding protein

Gene Ontology Categories:

Process(es)

neural tube closure
positive regulation of epithelial cell migration
actin cytoskeleton organization
negative regulation of actin filament polymerization
positive regulation of actin filament polymerization
negative regulation of actin filament bundle assembly
positive regulation of actin filament bundle assembly
positive regulation of ATPase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of viral transcription
protein stabilization
positive regulation of DNA metabolic process
positive regulation of stress fiber assembly
negative regulation of stress fiber assembly
Wnt signaling pathway, planar cell polarity pathway
cellular response to growth factor stimulus
cell-cell adhesion
positive regulation of ruffle assembly

Function(s)

adenyl-nucleotide exchange factor activity
actin binding
actin monomer binding
receptor binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
Rho GTPase binding
poly(A) RNA binding
proline-rich region binding
cadherin binding involved in cell-cell adhesion