45235

• Gene Symbol: MT3
• Gene Name: metallothionein 3
• Gene Aliases: GIF, GIFB, GRIF, ZnMT3
• Chromosome Location: Chr.16: 56589355 - 56591088 on Build GRCh38
• UniGene ID: Hs.73133
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MT3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005954.2	NP_005945.1	3	373
GenBank mRNA	BC013081.1	-	3	184	4152899
	BI752092.1	-		361
	BI820409.1	-		375
	BT007030.1	-	3	137
	CB155600.1	-	3	231
	D13365.1	-	3	189

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053968, S65838, X89603, BC058453.
This siRNA also targets the following transcripts in Mouse: NM_013603, AK140209, BC059725.

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
response to hypoxia
positive regulation of protein phosphorylation
energy reserve metabolic process
cholesterol catabolic process
zinc II ion transport
cellular metal ion homeostasis
cellular zinc ion homeostasis
apoptotic process
brain development
cell proliferation
response to metal ion
negative regulation of autophagy
positive regulation of gene expression
positive regulation of necrotic cell death
positive regulation of cell death
astrocyte development
histone modification
removal of superoxide radicals
negative regulation of cell growth
negative regulation of axon extension
positive regulation of vascular endothelial growth factor receptor signaling pathway
regulation of response to food
activation of protein kinase B activity
leptin-mediated signaling pathway
cellular response to oxidative stress
cellular response to drug
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
negative regulation of apoptotic process
positive regulation of catalytic activity
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
protein kinase B signaling
negative regulation of neuron apoptotic process
cellular lipid catabolic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
protein stabilization
negative regulation of oxidoreductase activity
zinc ion homeostasis
cadmium ion homeostasis
regulation of protein glycosylation
negative regulation of necrotic cell death
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
cellular response to cadmium ion
cellular response to hypoxia
cellular response to nitric oxide
positive regulation of lysosomal membrane permeability
negative regulation of cysteine-type endopeptidase activity
negative regulation of hydrogen peroxide catabolic process
positive regulation of oxygen metabolic process
negative regulation of reactive oxygen species metabolic process

Function(s)

copper ion binding
protein binding
drug binding
zinc ion binding
antioxidant activity
protein kinase activator activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
cadmium ion binding