4523

• Gene Symbol: TFAP2B
• Gene Name: transcription factor AP-2 beta
• Gene Aliases: AP-2B, AP2-B
• Chromosome Location: Chr.6: 50817692 - 50847619 on Build GRCh38
• UniGene ID: Hs.33102
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TFAP2B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003221.3	NP_003212.2	5	1034
	XM_011514837.2	XP_011513139.1	6	1339
	XM_017011233.1	XP_016866722.1	8	1715
	XM_017011234.1	XP_016866723.1	8	1168
	XM_017011235.1	XP_016866724.1	4	847
GenBank mRNA	AK291172.1	-	5	874
	AK313749.1	-	5	872
	BC037225.1	-	5	890	4745989
	X95694.1	-	5	867

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106896, XM_008766927, XM_006244649.
This siRNA also targets the following transcripts in Mouse: NM_001286340, NM_009334, NM_001025305, X78197, AK032045, and others.

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
kidney development
renal water homeostasis
glucose metabolic process
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
apoptotic process
positive regulation of cell proliferation
negative regulation of cell proliferation
response to lithium ion
retina layer formation
magnesium ion homeostasis
regulation of BMP signaling pathway
forelimb morphogenesis
hindlimb morphogenesis
positive regulation of urine volume
aorta morphogenesis
response to drug
glucose homeostasis
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
skin development
fat cell differentiation
regulation of cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
sympathetic nervous system development
regulation of insulin secretion
phosphate ion homeostasis
calcium ion homeostasis
potassium ion homeostasis
sodium ion homeostasis
distal tubule development
collecting duct development
metanephric nephron development
ductus arteriosus closure
cellular ammonia homeostasis
cellular creatinine homeostasis
cellular urea homeostasis

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
RNA polymerase II transcription corepressor activity
enhancer sequence-specific DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
transcription corepressor activity
protein binding
protein homodimerization activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
sequence-specific DNA binding
protein heterodimerization activity
protein dimerization activity