45938

Gene Symbol:

INS-IGF2 IGF2

Gene Name:

INS-IGF2 readthrough

insulin like growth factor 2

Gene Aliases:

INSIGF

C11orf43, GRDF, IGF-II, PP9974

Chromosome Location:

Chr.11: 2129112 - 2161209 on Build GRCh38

Chromosome Location:

Chr.11: 2129112 - 2149603 on Build GRCh38

UniGene ID:

Hs.272259

Hs.272259

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: INS-IGF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_003512.3		7	1058
GenBank mRNA	AK291594.1	-	4	447
	DQ104205.1	-	7	1062

Gene Symbol: IGF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000612.5	NP_000603.1	4	1096
	NM_001007139.5	NP_001007140.2	5	1070
	NM_001127598.2	NP_001121070.1	5	783
	NM_001291861.2	NP_001278790.1	4	447
	NM_001291862.2	NP_001278791.1	4	618
GenBank mRNA	AK126688.1	-		2946
	AK313938.1	-	4	448
	BC000531.1	-	4	868	2964584
	BT007013.1	-	3	344
	DQ104203.1	-	5	1074
	J03242.1	-	4	896
	M17426.1	-	4	680
	M17863.1	-	4	572
	M29645.1	-	4	594
	S77035.1	-	4	677
	X00910.1	-	4	594
	X06159.1	-	4	365
	X06160.1	-	4	441

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001122736, NM_010514, NM_001122737, BC053489, M14951, and others.

Panther Classification:

Molecular Function -

growth factor, intercellular signal molecule

Gene Ontology Categories:

Process(es)

skeletal system development
ossification
positive regulation of protein phosphorylation
platelet degranulation
glucose metabolic process
regulation of gene expression by genetic imprinting
regulation of transcription, DNA-templated
multicellular organism development
female pregnancy
memory
positive regulation of cell proliferation
insulin receptor signaling pathway
response to radiation
response to nutrient levels
response to estradiol
response to nicotine
insulin receptor signaling pathway via phosphatidylinositol 3-kinase
wound healing
positive regulation of activated T cell proliferation
response to drug
positive regulation of catalytic activity
positive regulation of MAPK cascade
cellular protein metabolic process
response to ethanol
positive regulation of glycogen biosynthetic process
positive regulation of mitotic nuclear division
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of insulin receptor signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of cell division
positive regulation of protein kinase B signaling
cellular response to mechanical stimulus
positive regulation of protein serine/threonine kinase activity
positive regulation of receptor activity
positive regulation of glycogen (starch) synthase activity

Function(s)

hormone activity
insulin receptor binding
insulin-like growth factor receptor binding
protein binding
growth factor activity
receptor activator activity
protein serine/threonine kinase activator activity