45946

• Gene Symbol: CRH
• Gene Name: corticotropin releasing hormone
• Gene Aliases: CRF, CRH1
• Chromosome Location: Chr.8: 66176377 - 66186685 on Build GRCh38
• UniGene ID: Hs.75294
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CRH
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000756.3	NP_000747.1	2	886
	XM_017013090.1	XP_016868579.1	6	1224
	XM_017013091.1	XP_016868580.1	6	1287
	XM_017013092.1	XP_016868581.1	6	1225
	XM_017013093.1	XP_016868582.1	6	1364
GenBank mRNA	AK075431.1	-	2	832
	BC002599.2	-	2	697	3160933
	BC011031.1	-	2	707	4280754
	BT007453.1	-	1	519
	KU177994.1	-	1	519
	KU177995.1	-	2	346

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031019, X03036.

Panther Classification:

Molecular Function -

peptide hormone

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
synaptic transmission, dopaminergic
glucocorticoid biosynthetic process
inflammatory response
signal transduction
chemical synaptic transmission
female pregnancy
parturition
learning or memory
positive regulation of cell proliferation
associative learning
hormone-mediated apoptotic signaling pathway
positive regulation of gene expression
negative regulation of gene expression
negative regulation of norepinephrine secretion
positive regulation of circadian sleep/wake cycle, wakefulness
positive regulation of cell death
regulation of serotonin secretion
diterpenoid metabolic process
hypothalamus development
lung development
adrenal gland development
positive regulation of cAMP biosynthetic process
negative regulation of epinephrine secretion
negative regulation of luteinizing hormone secretion
locomotory exploration behavior
positive regulation of insulin secretion involved in cellular response to glucose stimulus
response to immobilization stress
negative regulation of circadian sleep/wake cycle, REM sleep
response to drug
response to estrogen
response to ethanol
response to ether
negative regulation of blood pressure
response to pain
ion homeostasis
response to corticosterone
positive regulation of corticotropin secretion
positive regulation of cortisol secretion
long-term synaptic potentiation
positive regulation of digestive system process
negative regulation of cell death
negative regulation of glucagon secretion
cellular response to cocaine
cellular response to dexamethasone stimulus
positive regulation of calcium ion import
regulation of N-methyl-D-aspartate selective glutamate receptor activity
positive regulation of corticosterone secretion
positive regulation of behavioral fear response

Function(s)

receptor binding
hormone activity
neuropeptide hormone activity
protein binding
corticotropin-releasing hormone activity
corticotropin-releasing hormone receptor 1 binding
corticotropin-releasing hormone receptor 2 binding