46144

• Gene Symbol: SFN
• Gene Name: stratifin
• Gene Aliases: YWHAS
• Chromosome Location: Chr.1: 26863142 - 26864456 on Build GRCh38
• UniGene ID: Hs.523718
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SFN
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006142.3	NP_006133.1	1	197
GenBank mRNA	AF029082.1	-	1	197
	BC000329.2	-	1	177	2822397
	BC000995.2	-	1	174	3445915
	BC001550.1	-	1	179	3457665
	BC002995.1	-	1	177	2822397
	BC023552.2	-	1	201	3534328
	CR541905.1	-	1	126
	CR541926.1	-	1	126
	M93010.1	-	1	136

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

regulation of cyclin-dependent protein serine/threonine kinase activity
release of cytochrome c from mitochondria
keratinocyte development
negative regulation of protein kinase activity
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
signal transduction
intrinsic apoptotic signaling pathway in response to DNA damage
regulation of epidermal cell division
negative regulation of keratinocyte proliferation
positive regulation of cell growth
keratinization
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of epidermal cell differentiation
positive regulation of protein export from nucleus
membrane organization
establishment of skin barrier
negative regulation of protein serine/threonine kinase activity
cell-cell adhesion
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein binding
protein kinase C inhibitor activity
protein kinase binding
protein domain specific binding
phosphoprotein binding
cadherin binding involved in cell-cell adhesion