46591

• Gene Symbol: Pdgfa
• Gene Name: platelet-derived growth factor alpha polypeptide
• Gene Aliases: PDGFACP
• Chromosome Location: Chr.12: 17732358 - 17756186 on Build Rnor_6.0
• UniGene ID: Rn.10999
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pdgfa
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012801.1	NP_036933.1	4	601
	XM_006248918.2	XP_006248980.1	2	583
	XM_006248919.2	XP_006248981.1	2	583
	XM_008768940.1	XP_008767162.1	3	2182
GenBank mRNA	BC061731.1	-	2	588	5598667
	D10106.1	-	2	160
	L06238.1	-	4	601
	L06894.1	-	3	245
	Z14120.1	-	2	95

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008808, BC003817, AY324648, M29464.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

angiogenesis
response to hypoxia
hair follicle development
positive regulation of mesenchymal cell proliferation
transforming growth factor beta receptor signaling pathway
blood coagulation
positive regulation of cell proliferation
response to wounding
organ morphogenesis
response to organic substance
response to inorganic substance
negative regulation of phosphatidylinositol biosynthetic process
negative regulation of platelet activation
positive regulation of phosphatidylinositol 3-kinase signaling
regulation of smooth muscle cell migration
cell projection assembly
actin cytoskeleton organization
positive regulation of cell migration
positive regulation of protein autophosphorylation
response to estradiol
response to retinoic acid
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
wound healing
response to drug
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
skin development
positive regulation of DNA replication
platelet-derived growth factor receptor signaling pathway
positive regulation of fibroblast proliferation
lung alveolus development
digestive tract development
inner ear development
regulation of peptidyl-tyrosine phosphorylation
negative chemotaxis
positive regulation of cell division
positive regulation of protein kinase B signaling
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling
positive regulation of ERK1 and ERK2 cascade
regulation of glomerular mesangial cell proliferation
embryonic lung development
regulation of DNA biosynthetic process

Function(s)

platelet-derived growth factor receptor binding
collagen binding
growth factor activity
protein homodimerization activity
protein heterodimerization activity
platelet-derived growth factor binding