46655

• Gene Symbol: Pfn1
• Gene Name: profilin 1
• Gene Aliases: -
• Chromosome Location: Chr.10: 57273003 - 57275708 on Build Rnor_6.0
• UniGene ID: Rn.1152
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pfn1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022511.2	NP_071956.2	1	239
GenBank mRNA	BC062405.1	-	1	239	5623232
	FQ217736.1	-	1	273
	FQ221987.1	-	1	273
	FQ227505.1	-	1	274
	FQ228171.1	-	1	273
	FQ232047.1	-	1	272
	FQ232161.1	-	1	229
	FQ232713.1	-	1	243
	FQ232749.1	-	1	238
	FQ235292.1	-	1	274
	X96967.1	-	1	122

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011072, BC002080, AK028117, AK150780, AV448567, and others.

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein, cytoskeletal protein, non-motor actin binding protein

Gene Ontology Categories:

Process(es)

neural tube closure
regulation of transcription from RNA polymerase II promoter
actin polymerization or depolymerization
response to organic substance
positive regulation of epithelial cell migration
negative regulation of actin filament polymerization
positive regulation of actin filament polymerization
negative regulation of actin filament bundle assembly
positive regulation of ATPase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of viral transcription
positive regulation of DNA metabolic process
positive regulation of stress fiber assembly
negative regulation of stress fiber assembly
cellular response to growth factor stimulus
positive regulation of ruffle assembly

Function(s)

adenyl-nucleotide exchange factor activity
actin binding
receptor binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
Rho GTPase binding
poly(A) RNA binding
proline-rich region binding