46789

• Gene Symbol: Ccl3
• Gene Name: chemokine (C-C motif) ligand 3
• Gene Aliases: MIP-1a, Scya3
• Chromosome Location: Chr.10: 70869516 - 70871066 on Build Rnor_6.0
• UniGene ID: Rn.10139
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ccl3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013025.2	NP_037157.2	3	324
GenBank mRNA	EF121994.1	-	3	255
	EF121995.1	-	3	255
	U06435.1	-	3	255
	U22414.1	-	3	324

More Information

Panther Classification:

Molecular Function -

cytokine, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
osteoblast differentiation
cell activation
monocyte chemotaxis
protein phosphorylation
calcium ion transport
cellular calcium ion homeostasis
exocytosis
chemotaxis
inflammatory response
cytoskeleton organization
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
regulation of cell shape
response to toxic substance
positive regulation of gene expression
negative regulation of gene expression
T cell chemotaxis
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
calcium-mediated signaling
signaling
positive regulation of cell migration
negative regulation of bone mineralization
neutrophil chemotaxis
leukocyte chemotaxis
lipopolysaccharide-mediated signaling pathway
positive regulation of tumor necrosis factor production
response to drug
positive regulation of catalytic activity
eosinophil degranulation
protein kinase B signaling
positive regulation of neuron apoptotic process
astrocyte cell migration
negative regulation by host of viral transcription
negative regulation of osteoclast differentiation
positive regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
eosinophil chemotaxis
macrophage chemotaxis
lymphocyte chemotaxis
positive regulation of interleukin-1 beta secretion
positive regulation of inflammatory response
positive regulation of calcium-mediated signaling
positive chemotaxis
positive regulation of protein kinase B signaling
positive regulation of calcium ion transport
regulation of sensory perception of pain
cell chemotaxis
positive regulation of ERK1 and ERK2 cascade
response to cholesterol
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to organic cyclic compound
granulocyte chemotaxis
positive regulation of natural killer cell chemotaxis

Function(s)

protein kinase activity
calcium-dependent protein kinase C activity
chemokine activity
heparin binding
phospholipase activator activity
kinase activity
CCR1 chemokine receptor binding
CCR5 chemokine receptor binding
chemoattractant activity
identical protein binding