46863

• Gene Symbol: Ptgis
• Gene Name: prostaglandin I2 (prostacyclin) synthase
• Gene Aliases: PGIS
• Chromosome Location: Chr.3: 163950746 - 163986129 on Build Rnor_6.0
• UniGene ID: Rn.73051
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptgis
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031557.2	NP_113745.1		241
GenBank mRNA	BC061814.1	-		241	5598666
	U53855.1	-		172

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008968, AB001607, AK048059, BC062151, AK076585.

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
response to hypoxia
embryo implantation
negative regulation of NF-kappaB transcription factor activity
positive regulation of peroxisome proliferator activated receptor signaling pathway
regulation of apoptotic process
negative regulation of nitric oxide biosynthetic process
positive regulation of angiogenesis
decidualization
negative regulation of inflammatory response
oxidation-reduction process
cellular response to interleukin-1
cellular response to interleukin-6
cellular response to hypoxia
apoptotic signaling pathway
positive regulation of execution phase of apoptosis

Function(s)

monooxygenase activity
iron ion binding
prostaglandin-I synthase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
heme binding