4710

• Gene Symbol: TFAP2A
• Gene Name: transcription factor AP-2 alpha
• Gene Aliases: AP-2, AP-2alpha, AP2TF, BOFS, TFAP2
• Chromosome Location: Chr.6: 10396677 - 10419897 on Build GRCh38
• UniGene ID: Hs.519880
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TFAP2A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001032280.2	NP_001027451.1	7	1989
	NM_001042425.1	NP_001035890.1	7	1331
	NM_003220.2	NP_003211.1	7	1481
	XM_006715175.2	XP_006715238.1	7	1457
	XM_011514833.2	XP_011513135.1	8	1122
	XM_017011232.1	XP_016866721.1	7	1510
GenBank mRNA	BC017754.1	-	7	1989	4432023
	M36711.1	-	7	1291
	X52611.1	-	7	1291

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107345, XM_008771570.
This siRNA also targets the following transcripts in Mouse: NM_001122948, NM_011547, NM_001301674, AK013900, BC007471, and others.

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
kidney development
optic vesicle morphogenesis
optic cup structural organization
transcription from RNA polymerase II promoter
sensory perception of sound
negative regulation of cell proliferation
response to water deprivation
positive regulation of gene expression
retina layer formation
negative regulation of transcription by competitive promoter binding
Schwann cell development
trigeminal nerve development
oculomotor nerve formation
positive regulation of bone mineralization
response to lipopolysaccharide
embryonic forelimb morphogenesis
inner ear morphogenesis
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
regulation of cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic cranial skeleton morphogenesis
palate development
bone morphogenesis
eyelid development in camera-type eye
positive regulation of tooth mineralization
cellular response to iron ion
negative regulation of reactive oxygen species metabolic process

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription coactivator activity
protein binding
transcription factor binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity